Combined Transcriptomic and Metabolomic Analysis Reveals the Mechanism of Flavonoid Biosynthesis in Handroanthus chrysanthus (Jacq.) S.O.Grose

Handroanthus and Tabebuia are known for their ornamental medicinal value, which attributed to metabolites. However, the mechanisms underlying synthesis of these metabolites poorly understood. In this study, expression levels secondary mechanism flavonoid biosynthesis in bark leaves chrysantha (Jaq.) were examined using transcriptomic metabolomic techniques. Metabolic analysis identified several differentially accumulated (DAMs), most flavonoids, isoprenoids, sterols. Additionally, 30 flavonoids H. chrysantha. Transcriptomic 69 genes involved biosynthesis, among 49 significantly different between leaves. qRT-PCR eight showed that patterns consistent with transcriptome sequencing data. Integrative 20 expressed (DEGs) associated strongly correlated seven DAMs, confirming involvement DEGs biosynthesis. These findings considerably contribute understanding serve as a reference further pharmacological studies.